First let me state that I have been using the Palm Desktop for the better part of seventeen (17) years. There was a short period of time where I used J-Pilot, but I preferred the Palm Desktop. That was when I found that version 3.0.1 (the one that comes on the Handspring CD) worked quite well using WINE. The one drawback, is that you have to use a serial cradle for syncing. Just recently had to upgrade my OS and had an issue getting my Handspring Visor to sync. It turned out to be a permissions issue regarding the serial port. I know this is ancient technology, but it still does what I need done and I like it. Plus, I feel that my data is just a bit more private. Who really knows just what your cell phone is handing out these days? Here is my setup and installation, etc.: Dell Latitude D620, 4 gig memory Linux Mint 18.1 32 bit (edit) -> Mate Desktop WINE from repository Handspring Install CD After installing the Palm Desktop I could not get my Visor to sync. I didn’t recall having to do anything special on my older install, and was at a loss. After several hours of searching the internet, I found a piece of something that led to the solution. The thing to remember is that everything is a file in linux. Found that by changing the permission on /dev/ttyS0 allowed for syncing. So, added the following line to /etc/rc.local: chmod 777 /dev/ttyS0 Rebooted to be sure that I could still sync and found that all was good. Now, I don’t have any experience with an USB-to-Serial, but might have a similar issue. I also don’t know if there is a way to get a USB Cradle to work with the Palm Desktop using WINE or not. I had a Serial Cradle, so no need to fight with it. Serial Cradles can still be found on flea bay and Amazon. Just thought I would pass this on, in case there are some other die hards like me or maybe some of the younger generation looking for a more simple solution to organization.